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Article
Recent approaches in designing bioadhesive materials inspired by mussel adhesive protein
Journal of Polymer Science, Part A: Polymer Chemistry
  • Pegah Kord Forooshani, Michigan Technological University
  • Bruce P. Lee, Michigan Technological University
Document Type
Article
Publication Date
10-11-2016
Abstract

Marine mussels secret protein-based adhesives, which enable them to anchor to various surfaces in a saline, intertidal zone. Mussel foot proteins (Mfps) contain a large abundance of a unique, catecholic amino acid, Dopa, in their protein sequences. Catechol offers robust and durable adhe-sion to various substrate surfaces and contributes to the curing of the adhesive plaques. In this article, we review the unique features and the key functionalities of Mfps, catechol chemistry, and strategies for preparing catechol-functionalized poly- mers. Specifically, we reviewed recent findings on the contributions of various features of Mfps on interfacial binding, which include coacervate formation, surface drying properties, control of the oxidation state of catechol, among other features. We also summarized recent developments in designing advanced biomimetic materials including coacervate-forming adhesives, mechanically improved nano- and micro-composite adhesive hydrogels, as well as smart and self-healing materials. Finally, we review the applications of catechol-functionalized materials for the use as biomedical adhesives, therapeutic applications, and antifouling coatings.

Publisher's Statement

© 2016 The Authors. Published by Wiley Periodicals, Inc. Deposited here in compliance with publisher policies.

Creative Commons License
Creative Commons Attribution-Noncommercial-No Derivative Works 4.0
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Publisher's PDF
Citation Information
Pegah Kord Forooshani and Bruce P. Lee. "Recent approaches in designing bioadhesive materials inspired by mussel adhesive protein" Journal of Polymer Science, Part A: Polymer Chemistry (2016)
Available at: http://0-works.bepress.com.library.simmons.edu/bruce-lee/46/